Determination of urinary marker proteins was carried out, trying to evaluate renal tubular damage as a part of renal injury caused by ESWL via EDAP LT-01+lithotriptor. All of twenty patients undergoing ESWL, suffered from unilateral,
nonobstructive,
infection-free, and previously untreated renal stone(s). Two urinary marker proteins, N-acetyl-beta-glucosaminidase(NAG) and beta 2-microglobulin (β2-M) were monitored in all the patients 1 day before, 1 and 3day(s) after ESWL using total 100
storage
of 3 sessions which is average therapeutical dose. Urinary level of NAG (normal value; 0.29-7.23 U/L) was 1.66±1.31 1 day before. 1.97±1.57, 2.66±2.90 U/L 1 and 3 day (s) after ESWL respectively. β2-M level (normal value<300 ug/L) was
142±137
1 day
before, 133±100, 151±186 ug/L 1 and 3 day (s) after FSWL, respectively. Consequently it was concluded that ESWL using average therapeutical dose (100 stage) via EDAP LT-01+lithotriptor can hardly develop renal tubular damage.
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